Fig. 1: Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) is expressed at high levels in papillary thyroid cancer (PTC) and is associated with poor prognosis of PTC patients. | Cell Death & Disease

Fig. 1: Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) is expressed at high levels in papillary thyroid cancer (PTC) and is associated with poor prognosis of PTC patients.

From: Prolyl 4-hydroxylase subunit alpha-2 acts as a TRIM21 ubiquitination substrate to promote papillary thyroid cancer progression via the glycolytic pathway

Fig. 1

A Venn plot of differentially expressed genes (DEGs) for four Gene Expression Omnibus (GEO) PTC data sets. B Disease-free survival analysis of DEGs in PTC. C Boxplot of seven DEGs associated with poor prognosis in PTC. D Expression of P4HA2 in normal tissues and PTC tumors derived from the Human Protein Atlas (HPA) database. E Relative P4HA2 mRNA expression levels in healthy human thyroid cells and PTC cells. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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