Fig. 4: AKR1C3 is associated with ferroptosis. | Cell Death & Disease

Fig. 4: AKR1C3 is associated with ferroptosis.

From: AKR1C3 enhances radioresistance in esophageal adenocarcinoma via inhibiting ferroptosis through suppressing TRIM21-mediated ubiquitination of HSPA5

Fig. 4: AKR1C3 is associated with ferroptosis.The alternative text for this image may have been generated using AI.

A KEGG pathways ranked by fold enrichment were analyzed based on the DEGs of OE33P/OE33R. B Venn diagram analysis illustrated the five genes overlapped between 238 ferroptosis suppressors and 375 DEGs of OE33P/R. C KEGG pathways ranked by fold enrichment were analyzed based on the DEGs of the AKR1C3 high/low group from the TCGA EAC cohort. D KEGG pathways ranked by fold enrichment were analyzed based on the DEGs of the AKR1C3 high/low group from scRNA-seq.

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