Fig. 3: Overview of ESCC-infiltrated macrophages characterized by scRNA-seq.

A Heatmap displaying the expression of marker genes within each macrophage cluster. B–D Dot plots showing the enriched pathways across different macrophage clusters. E Pie chart showing the proportion of each macrophage cluster derived from the sample source. F Dot plots depicting the enrichment scores of each gene set across various macrophage sub-clusters. G Dot plots comparing the enrichment scores of each gene set across macrophage sub-clusters originating from PR, SD, and surgical tumors. H Dot plots highlighting the differentially enriched pathways in cluster 6 macrophages between PR and SD tumors.