Fig. 1: TFIIB-related factor 2 (BRF2) was highly expressed in lung squamous cell carcinoma tissues and lung cancer cell lines. | Cell Death & Disease

Fig. 1: TFIIB-related factor 2 (BRF2) was highly expressed in lung squamous cell carcinoma tissues and lung cancer cell lines.

From: TFIIB-related factor 2 inhibits lung squamous carcinoma cell apoptosis through SLC8A3-mediated mitochondrial homeostasis

Fig. 1

A BRF2 mRNA expression level in lung squamous carcinoma was higher than in normal tissues according to the Cancer Genome Atlas dataset. Red: tumor; black: normal; and ***P < 0.001. B BRF2 expression in LUSC cell lines (H520 and H226) was higher than in human normal bronchial epithelial cells (HBE) and human normal lung epithelial cells (BEAS-2B). C Representative IHC images demonstrating the expression level of BRF2 in LUSC tissues and normal tissues. D The IHC scores of BRF2 in LUSC tissues were higher than normal lung tissues (****P < 0.0001).

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