Fig. 6: IFFO1 and IQGAP3 interaction is responsible for cell migration and mobility. | Cell Death & Disease

Fig. 6: IFFO1 and IQGAP3 interaction is responsible for cell migration and mobility.

From: Intermediate filament IFFO1 negatively regulates the migration of lung cancer cells by inhibiting the IQGAP3-Cdc42 interaction

Fig. 6: IFFO1 and IQGAP3 interaction is responsible for cell migration and mobility.The alternative text for this image may have been generated using AI.

Clone formation A, the migration B, Western blotting of N-cadherin, Vimentin, and PI3K/Akt signaling pathway C, immunofluorescence staining of N-cadherin D, and speed and total distance during the recorded 175 min E after re-expression of full-length IFFO1 and the mutant losing IQGAP3 interaction (∆2 A) in IFFO1−/− cells. The scale bars are 100 μm (B) and 30 μm (D), respectively. *p < 0.05. **p < 0.01. ***p < 0.001. NS, not significant.

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