Fig. 2: SORT1 promotes hepatocellular carcinoma cell migration and invasion in vitro. | Cell Death & Disease

Fig. 2: SORT1 promotes hepatocellular carcinoma cell migration and invasion in vitro.

From: SORT1 promote the metastasis and invasion of hepatocellular carcinoma via p38/β-catenin/ZEB1 signaling pathway

Fig. 2

A SORT1 was silenced in SMMC-7721 and Huh-7 cells by siRNAs. B SORT1 was overexpressed by transfecting pcDNA3.1-SORT1 plasmids in SMMC-7721 and Huh-7 cells. Transwell assays detected the invasion and migration abilities in cells with SORT1 depletion C or overexpression (D). Representative images and the quantitative data of three randomly selected fields are shown. Wound-healing assays measuring cell motility in SORT1-knockdown (E) and SORT1-expressing cells (F). Scale bar = 200 μm. Quantitative data are presented as the mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001.

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