Fig. 2: ATM knockdown is expected to improve the immune “heat” of TNBC. | Cell Death & Disease

Fig. 2: ATM knockdown is expected to improve the immune “heat” of TNBC.

From: Inhibition of ATM enhances the immunogenicity of triple-negative breast cancer by promoting MHC-I expression

Fig. 2

A–H Representative dot plots (left) and statistical analysis (right) of CD8+ T cells (A–D), CD8+ T cells exhaustion (E–H) cocultured with the indicated cell line. *P < 0.05 and **P < 0.01, by unpaired t test. The experiments were performed and repeated at least three times, independently. I The killing efficiency of different proportions of CD8+ T cells to tumor cells was detected by LDH killing kit. Error bars represent mean ± SD. *P < 0.05 and **P < 0.01, two-way analysis of variance (ANOVA).

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