Fig. 6: The expression of SYVN1 in NSCLC tissues is positively correlated with EGFR and negatively associated with prognosis.
From: Targeting the SYVN1-EGFR axis: a breakthrough strategy for TKI-resistant NSCLC
A–D The mRNA levels of SYVN1 (A, B) and EGFR (C, D) in NSCLC and normal lung tissues were analyzed through the TCGA database. E, F SYVN1 and EGFR proteins are highly expressed in NSCLC tissues compared to normal tissues. G, H IHC staining analysis of SYVN1 and EGFR was performed in NSCLC tissue microarrays, and representative IHC staining images are shown. I The IHC scores of SYVN1 and EGFR in (G, H). J The correlation analysis was conducted between SYVN1 and EGFR scores using Spearman’s correlation coefficient. K Kaplan−Meier plots of overall survival (OS) for patients with tissue microarrays.
