Fig. 8: Circulating epigenetic markers in PBMCs from CRC patients and control group (CTRL).

A Expression of a panel of miRNA in PBMCs from CTRL and CRC subjects. The histograms show 2^-ΔCt levels of differentially expressed miRNAs. Data are mean ± Standard Errors; *p < 0.05 vs CTRL. B DNA methylation analysis of PON3 in PBMC samples from CTRL and CRC subjects. The DNA methylation status is expressed as percentage of CpG methylation. Data are mean ± Standard Errors. *p < 0.05 vs. CTRL subjects. (n = 48 CTRL and n = 102 CRC).