Fig. 4: FBP2 has the capability to inhibit aerobic glycolysis in GC cells. | Cell Death & Disease

Fig. 4: FBP2 has the capability to inhibit aerobic glycolysis in GC cells.

From: The regulatory and synergistic effects of FBP2 and HKDC1 on glucose metabolism and malignant progression in gastric cancer

Fig. 4: FBP2 has the capability to inhibit aerobic glycolysis in GC cells.The alternative text for this image may have been generated using AI.

A The glucose uptake rate, B ATP synthesis, C lactic acid (LA), D and pyruvate acid (PA) production of FBP2 and Vector cells were measured and compared using ultraviolet spectrophotometry. E Impact of FBP2 on the expression levels of key glycolytic proteins in GC cells. Line chart depicting the alterations in glycolytic pressure in F BGC-823 and G AGS GC cells with FBP2 overexpression. H Analysis of nonglycolytic acidification, I glycolysis, J glycolytic capacity, and K glycolytic reserve between FBP2 and Vector GC cells using extracellular acidification rate (ECAR) analysis. “FBP2 cells” refers to cell lines that overexpress FBP2. Data are presented as the mean ± standard deviation, n = 3. *P < 0.05, **P < 0.01, ***P < 0.001.

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