Fig. 9: Analysis of the synergistic regulatory mechanism of FBP2+sh-HKDC1 on GC. | Cell Death & Disease

Fig. 9: Analysis of the synergistic regulatory mechanism of FBP2+sh-HKDC1 on GC.

From: The regulatory and synergistic effects of FBP2 and HKDC1 on glucose metabolism and malignant progression in gastric cancer

Fig. 9: Analysis of the synergistic regulatory mechanism of FBP2+sh-HKDC1 on GC.The alternative text for this image may have been generated using AI.

A Volcano plot and B heatmap generated from the RNA sequencing data of FBP2+sh-HKDC1 and Vector+sh-NC cells, along with C PPI network constructed based on the top 10 significant DEGs. D GO and E KEGG pathway enrichment analysis was performed based on the DEGs. F Differentially expressed transcription factor families and their corresponding gene members. G Impact of FBP2+sh-HKDC1 on the expression levels of key glycolytic proteins in GC cells. H Schematic illustration of the synergistic regulatory mechanism of FBP2 and sh-HKDC1 on glucose metabolism in GC.

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