Fig. 5: ALIX overexpression reduces N-GSDMD level and pyroptosis susceptibility. | Cell Death & Disease

Fig. 5: ALIX overexpression reduces N-GSDMD level and pyroptosis susceptibility.

From: ALIX mediates reversible gasdermin-D pore formation via the endosomal pathway to limit pyroptosis by active membrane repair

Fig. 5

A Immunoblot of ALIX overexpressing THP-1 cells treated with 500 ng/ml alpha toxin at time points 8,12, and 24 h. B Immunoblot of ALIX overexpressing HeLa cells treated with 500 ng/ml alpha toxin at time points 8,12, and 24 h. Actin was used as internal loading control. C Flow cytometry detection of ALIX overexpressing THP-1 cells 1 h after 500 ng/ml alpha toxin treatment. Percentages indicate the cells showing high PI intensity (PI uptake).

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