Table 1 Relationship between OTUB1 expression and clinicopathological features.

From: The deubiquitylase OTUB1 drives gemcitabine resistance in pancreatic cancer by enhancing pyrimidine metabolism through modulating DHODH mRNA stability

Parameters

Group

n

OTUB1 expression

P value

Low (N = 28)

High (N = 58)

Age (years)

    

P = 0.1186

 

Male

56

15

41

 
 

Female

30

13

17

 

Gender

    

P = 0.1916

 

≤65

23

10

13

 
 

Ã¥ 65

63

18

45

 

T

    

P = 0.1635

 

T1–T2

65

15

40

 
 

T3-T4

21

13

18

 

N

    

P = 0.3607

 

0

31

12

19

 
 

1–2

55

16

39

 

M

    

P = 0.7859

 

0

57

18

39

 
 

1

29

10

19

 

Stage

    

P = 0.0027

 

IA–IIB

58

25

33

 
 

Ⅲ–Ⅳ

28

3

25

 

Tumor size

    

P = 0.0213

 

≤3

49

11

38

 
 

>3

37

17

20

 

Distant metastasis

    

P = 0.7902

 

No

66

21

45

 
 

Yes

20

7

13

 

Differentiation

 

Well

Moderate/poor

29

57

23

5

23

35

P = 0.0002

  1. Bold values indicate significant differences.