Fig. 1: Overexpression of TRIM8 is correlated with vessel density in human GC tissues and predicts a poor prognosis. | Cell Death & Disease

Fig. 1: Overexpression of TRIM8 is correlated with vessel density in human GC tissues and predicts a poor prognosis.

From: TRIM8-dependent K63-ubiquitinated PGK1 promotes glycolysis and angiogenesis in gastric cancer via interaction with ACAT1

Fig. 1

A, B The expression of genes encoding E3 ubiquitin ligase in the TRIM family in TCGA dataset. C–G Correlation analysis of TRIM8, TRIM9, TRIM28, TRIM47, TRIM69 and vessel density in GC. H Overexpression of TRIM8 mRNA in GC tissues than normal tissues in TCGA dataset. I The overall survival analysis was plotted using Kaplan–Meier Plotter for patients with GC. J The disease-free survival analysis was plotted using Kaplan–Meier Plotter for patients with GC. K TRIM8 expression level in GC tissues and adjacent non-tumor tissues detected by qRT-PCR. ***, p < 0.001. L TRIM8 expression level in GC tissues and adjacent non-tumor tissues was detected by western blot. M Representative IHC staining for TRIM8 in GC and adjacent nontumor tissues. N Quantification of M. *, p < 0.5. O Representative IHC staining for PECAM1 in GC and adjacent nontumor tissues. P Quantification of O. **, p < 0.01. Q Correlation analysis of TRIM8 and vessel density in GC.

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