Fig. 6: Impact of C3G deficiency in hepatocytes on the expression of enzymes involved in fatty acid metabolism and ketogenesis.
From: Deletion of C3G in hepatocytes impairs full liver maturation and alters glucose homeostasis
A RT-qPCR analysis of Acaca, Fasn, and Hmgcs2 mRNA expression in the liver of 1-month-old C3GKOAlb and wt mice. B Western blot analysis of FAS, P-ACC, ACC, and CPT1A protein levels in livers from C3GKOAlb and wt mice normalized with β-actin or α-Tubulin (left panel). Histograms show the quantification of different western blots (right panel). C Histogram showing serum levels of beta-hydroxy-butyrate. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 compared to wt mice (n = 2–15).
