Table 1 Univariate and multivariate Cox regression of overall survival for patients with PDAC.

From: m6A demethylase FTO drives pancreatic ductal adenocarcinoma tumorigenesis and metastasis through remodeling PFKM mediated glycolysis

 

Univariate

Multivariate

Characteristics

HR

95%CI

P

HR

95%CI

P

Age

      

 <60

1

0.720–1.427

0.937

   

 ≥60

1.206

     

Gender

      

 Female

1

0.719–1.348

0.923

   

 Male

0.985

     

Perineural invasion (PNI)

      

 Negative

1

0.733–2.83

0.289

   

 Positive

1.441

     

Lymph node status

      

 Negative

1

1.037–1.969

0.029

   

 Positive

1.429

     

Tumor embolus

      

 Negative

1

1.271–2.412

<0.001

1

1.119–2.226

0.009

 Positive

1.751

  

1.578

  

CA199 level (u/ml)

      

 <200

1

1.081–2.048

0.015

1

1.024–1.975

0.036

 ≥200

1.488

  

1.422

  

Tumor size (cm)

      

 <4

1

1.116–2.241

0.009

1

1.057–2.196

0.024

 ≥4

1.582

  

1.524

  

PFKM expression

      

 Low

1

1.079–2.156

0.017

1

1.163–2.37

0.005

 High

1.525

  

1.66

  
  1. Univariate P values were derived with log-rank test. Multivariate P values were derived with Cox regression analysis, CI indicates confidence interval; HR hazard ratio.
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