Fig. 8: The mechanism of YTHDC2’s function in bladder cancer.
From: YTHDC2 suppresses bladder cancer by inhibiting SOX2-mediated tumor plasticity

A working model to illustrate how YTHDC2 inhibit tumor progression by down-regulating transcription factor SOX2 and restrain the CSC pool and EMT plasticity induced by SOX2. The working model was created in BioRender.com.