Fig. 7: PKM2 inhibitor partly reversed the protective effect of USP7 knockdown on SAP. | Cell Death & Disease

Fig. 7: PKM2 inhibitor partly reversed the protective effect of USP7 knockdown on SAP.

From: Ubiquitin-specific protease 7 regulates macrophage polarization via pyruvate kinase M2-mediated metabolic reprogramming in severe acute pancreatitis

Fig. 7

A Serum amylase and lipase activities from the ELISA. B IL-1β, TNF-α, IL-6 mRNA expression in pancreatic tissues from the results of qPCR. C Serum concentrations of IL-1β, TNF-α and IL-6 from the ELISA. D Pancreatic tissue damage according to the HE staining. n = 6. *p < 0.05, **p < 0.01, ***p < 0.001.

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