Fig. 5: Epigenetic modifications promote sorafenib resistance through metabolic reprogramming, involving the following regulators. | Cell Death & Disease

Fig. 5: Epigenetic modifications promote sorafenib resistance through metabolic reprogramming, involving the following regulators.

From: Resistance of first-line targeted drugs in hepatocellular carcinoma: the epigenetic regulation mechanisms

Fig. 5

a miR-374b, miR-188-5p, miR-30a-5p, and miR-494 promote resistance by regulating glycolysis. b lncRNA LINC01468 and lncRNA LINC01056 promote resistance by regulating lipid metabolism. c lncRNA LINC01234 promotes resistance by regulating aspartate metabolism. Image created by Figdraw.

Back to article page