Fig. 1: Impact of local mRNA expression of various genes coding for fatty acid binding proteins on patient prognosis across different cancers in the TCGA database.
A Differential gene expression across cancer types. Fold change (FC) was calculated based on mean gene expression (log2 (TPM + 1)) in tumor (T) versus non-tumor (NT). The log10-transformed FC is presented in the heatmap. P values were calculated by means of the Wilcoxon rank sum test. B Kaplan–Meier survival analyses of gene mRNA expression across distinct cancers. Overall survival (OS) was calculated using the log-rank test, with patients stratified into high and low expression groups based on the median gene expression level (log₂ (TPM + 1)) for each cancer type. The log₂-transformed hazard ratio (HR) is presented in the heatmap. *P < 0.05, **P < 0.01. The data were obtained from the UCSC Xena platform (https://xenabrowser.net/datapages/), incorporating tumor samples from The Cancer Genome Atlas (TCGA) and non-tumor samples from the Genotype-Tissue Expression (GTEx) project.
