Fig. 2: Viral tracing reveals the multisynaptic circuit of VGlut2 neurons in the fasting-activated state. | Cell Death & Disease

Fig. 2: Viral tracing reveals the multisynaptic circuit of VGlut2 neurons in the fasting-activated state.

From: Paraventricular nucleus–locus coeruleus VGlut2 neural circuit regulates energy metabolism in mice

Fig. 2: Viral tracing reveals the multisynaptic circuit of VGlut2 neurons in the fasting-activated state.The alternative text for this image may have been generated using AI.

A Schematic diagram of PRV injection into iBAT of diet-induced obese mice (left). PVH virus expression (right). B Distribution of fluorescent signals in the midbrain and brainstem. C Quantitative analysis of the total number of upstream neurons labelled by PRV, c-Fos, and VGlut2. n = 5 mice. Two-way ANOVA, Šídák’s test. Data are presented as mean ± standard error of mean (s.e.m). iBAT dorsoscapular brown adipose tissue, PVH paraventricular nucleus of the hypothalamus.

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