Fig. 1: Cervical metastatic lymph nodes of head and neck carcinoma are enriched with triglyceride. | Cell Death & Disease

Fig. 1: Cervical metastatic lymph nodes of head and neck carcinoma are enriched with triglyceride.

From: Necrotic and apoptotic adipocytes in the hypoxic tumor microenvironment supply triglycerides to induce cisplatin resistance in the metastatic lymph nodes of head and neck carcinoma

Fig. 1

A OPLS-DA-Score plot showed the overall differences in lipid profile of primary sites and metastatic neck nodes (n = 21). B Lipid classification of all differential lipids using lipidmaps. C Heatmap of differential lipids, identified by FC > 2, P < 0.001, VIP > 1.5. D Pathway enrichment analysis using the Lipid Ontology. E Lipid structural characteristic heatmap of triglycerides. F The typical images and quantitative analysis of oil red O stain area of tumor tissues from the primary sites and metastatic neck nodes in three patients. PS: primary site. MLN: metastatic lymph node. means ± SEM.*P < 0.05, ‌**P < 0.01, ‌***P < 0.001, ****P < 0.0001, ns no statistical significance.

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