Fig. 3: CREB3L2 facilitates HCC cell proliferation and metastasis in vivo.

A, B Subcutaneous tumor volume and weight changes were evaluated in mice after manipulating CREB3L2 expression (knockdown or overexpression). C, D The effects of CREB3L2 knockdown or overexpression on the nude mice model of pulmonary metastasis. *P < 0.05; **P < 0.01; ***P < 0.001.