Fig. 7: Association of TLR3 with immune infiltration and prognostic value of combined TRIM3/TLR3 expression in NSCLC. | Cell Death & Disease

Fig. 7: Association of TLR3 with immune infiltration and prognostic value of combined TRIM3/TLR3 expression in NSCLC.

From: The TRIM3/TLR3 axis overrides IFN-β feedback inhibition to suppress NSCLC progression

Fig. 7

A–H Bioinformatic analysis was conducted to evaluate the correlations between TLR3 expression and the immune infiltration levels of CD4⁺ T cells, M1 macrophages, M2 macrophages and NK cells in LUAD and LUSC. I Kaplan–Meier survival curves were plotted to correlate the combined TRIM3 and TLR3 mRNA expression with the overall survival of patients with NSCLC. The log-rank test was used for statistical analysis. J Schematic diagram depicting the mechanism by which the TRIM3/TLR3 axis overrides IFN-β feedback inhibition to suppress NSCLC progression.

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