Fig. 2: Macrophages reduce lipid peroxide in cells undergoing ferroptosis.

BODIPY-labeled cells were treated as in Fig. 1a and then analyzed by flow cytometry. a Representative flow cytometric histogram of control BeWo cells and cells treated with RSL3. b Graphs illustrate the quantitative analysis of C11-BODIPY signal intensity at the indicated time points during ferroptosis based on flow cytometry experiments. Time 0 refers to the cells immediately after RSL3 pretreatment and before the addition of either Fer1 or macrophages to the culture. Representative of three independent experiments is shown.