Fig. 3: Knockdown of NAT10 inhibits migration and invasion of GBM cells in vitro. | Cell Death & Disease

Fig. 3: Knockdown of NAT10 inhibits migration and invasion of GBM cells in vitro.

From: NAT10-mediated N4-acetylcytidine (ac4C) modification of PIK3R2 mRNA promotes malignant progression of glioblastoma

Fig. 3

A–I Transwell assays were performed to assess the migration and invasion abilities of GBM cells following NAT10 knockdown or treatment with Remodelin (20 μM for 24 h). J, K Western blot analysis of FN1, N-cadherin, Vimentin, and Snail expression in U87 and LN229 cells after NAT10 knockdown. L, M Western blot analysis of FN1, N-cadherin, Vimentin, and Snail expression in GBM cells treated with Remodelin (20 μM for 24 h). Error bars represent the mean ± SD. n = 3. ***p < 0.001. (Student’s t test).

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