Fig. 3: Ablation of Chm in the retina significantly attenuated visual function.
From: Deficiency disrupts photoreceptor viability and synaptic integrity in a choroideremia mouse model
A Representative ERG traces elicited by scotopic conditions at a flash intensity of 0.1 cd•s/m2. B The plot of scotopic ERG a-wave and b-wave amplitudes elicited from Chmfl/y; Six3-Cre mouse and littermate controls were recorded at P30. (mean ± SEM, n = 10; *: P < 0.05, **: P < 0.01, ***: P < 0.001, ns: no significance). C Representative ERG traces elicited by photopic conditions at a flash intensity of 100 cd•s/m2. D The plot of photopic ERG a-wave and b-wave amplitudes elicited from Chmfl/y; Six3-Cre mouse and littermate controls were recorded at P30. (mean ± SEM, n = 10; ***: P < 0.001, ns: no significance).
