Fig. 5: REP1 deficiency decreases key PR and ON BC mRNA transcripts.
From: Deficiency disrupts photoreceptor viability and synaptic integrity in a choroideremia mouse model
A The expression levels of PR transcription factors from retinal extracts between Chmfl/y; Six3-Cre mouse and littermate controls are represented as a heat map. B Transcript-level differential expression of PR (Rcvrn, Opn1sw, Rho), BC (Prkca), synapse (Grm6, Cabp4, Ctbp2) related genes was confirmed by RT-PCR between Chmfl/y; Six3-Cre mouse and littermate controls at P14 (mean ± SEM, n = 5; *: P < 0.05; **: P < 0.01; ***: P < 0.001, ns: no significance).
