Fig. 6: Smad3 promotes malignant phenotypes of bladder cancer cells in vitro. | Cell Death & Disease

Fig. 6: Smad3 promotes malignant phenotypes of bladder cancer cells in vitro.

From: Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells

Fig. 6

A–D The effect of Smad3 knockdown on cell migration was demonstrated by scratch healing assay. E–H The effect of Smad3 knockdown on migratory and invasive abilities was demonstrated by transwell migration and invasion assay. I–K The effect of Smad3 knockdown on clones formation abilities was demonstrated by colony formation assays. L Cell death analysis of Smad3-knockdown mesenchymal-like bladder cancer cells via flow cytometry. Data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, not significant (p > 0.05).

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