Fig. 2: Recognition memory is differentially impaired between males and females during aging. | Cell Death & Disease

Fig. 2: Recognition memory is differentially impaired between males and females during aging.

From: Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice

Fig. 2: Recognition memory is differentially impaired between males and females during aging.

Behavioral performance was evaluated using the NOR and NOL tests. The left panel visually represents the test phase; the middle panel shows the recognition index for NOR and NOL tests, and the right panel shows representative track plots. A The familiarization phase showed no discrepancies in object exploration. B NOR phase shows that aged females had no preference for the novel object, while (C) NOL phase shows that aged males had no preference for the novel localization of the object. Values represent means ± SEM. Statistical differences were calculated by two-way ANOVA. *p < 0.05, **p < 0.01.

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