Fig. 7: TPI1 enhances Gem-induced mitophagy in BCa tissues. | Cell Death & Disease

Fig. 7: TPI1 enhances Gem-induced mitophagy in BCa tissues.

From: TPI1 enhances gemcitabine resistance in bladder cancer by promoting autophagy through activating Beclin-1

Fig. 7

A, B Western blot analysis of p62 and TOM20 expression in subcutaneous tumor tissues from different groups of nude mice and quantification. C, D Western blot analysis of p62 and TOM20 expression in chemotherapy-resistant human BCa tissues grouped into high TPI1 expression (HTEG) and low TPI1 expression (LTEG) and quantification. E, F Immunohistochemical staining of p62 and TOM20 in HTEG and LTEG and quantification. Data are presented as mean ± SD from three independent experiments. P values in (B) were calculated by one-way ANOVA with Tukey’s multiple comparisons test. P values in (D, F) were calculated using a two-tailed unpaired Student’s t test.

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