Fig. 2: Knockdown of IRX3 inhibits cell proliferation in GBM. | Cell Death & Disease

Fig. 2: Knockdown of IRX3 inhibits cell proliferation in GBM.

From: IRX3-CDK14 axis promotes glioblastoma progression by regulating LRP6-mediated canonical Wnt/β-catenin pathway

Fig. 2: Knockdown of IRX3 inhibits cell proliferation in GBM.

A, B Immunoblotting analysis and qRT-PCR analysis of IRX3 expressions in LN229 and GBM02 cells stably expressing IRX3 shRNA or a control shRNA. C Representative microscopical images of GBM cells with or without IRX3 knockdown. D, E Cell viabilities of GBM cells with or without IRX3 knockdown were determined by CCK-8 assay. Data were presented as means and SD (n = 3), **p < 0.01. F, G Representative immunofluorescence images and quantifications of Edu staining in GBM cells with IRX3 knockdown or control. H Representative microscopical images of colony formation in GBM cells with IRX3 knockdown or control.

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