Table 1 Donor characteristics of tissues used for senescence associated secretory phenotype (SASP) study.

From: p16-mediated G0/G1 cell cycle arrest leads to SASP and fibrosis in Fuchs endothelial corneal dystrophy

 

Age (years)

Sex

Death to preservation time (hr:min)

ECD (cells/mm2)

COD

SA-β-Gal + RT-PCR (Control SASP)

54

M

22:22

1704

Myocardial infarction

50

M

12:0

3040

Myocardial infarction

54

F

8:1

2985

Anoxia

56

M

24:38

2801

Cardiac arrest

SA-β-Gal + RT-PCR (Acute SASP)

55

M

23:08

1767

Myocardial infarction

66

F

8:43

2717

Alcoholic liver disease

55

M

23:08

1642

Myocardial infarction

64

F

5:39

3012

Lung Cancer

SA-β-Gal + RT-PCR (Chronic SASP)

66

F

8:43

2591

Alcoholic liver disease

54

F

8:1

3115

Anoxia

56

F

15:22

1927

Myocardial infarction

54

F

19:5

2222

Pancreatitis

  1. M male, F female, ECD endothelial cell density, COD cause of death, RT-PCR reverse transcription polymerase chain reaction, SA-β-Gal Senescence-associated beta-galactosidase. Each donor tissue was divided in equal half.
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