Fig. 4: Characterization of cell cycle genes in hPSC differentiation into pancreatic β-like cells. | Cell Death & Disease

Fig. 4: Characterization of cell cycle genes in hPSC differentiation into pancreatic β-like cells.

From: RNA-seq at different stages of human pancreatic β cell differentiation reveals proliferation dynamics and SMAD9 in directing β cell fate

Fig. 4: Characterization of cell cycle genes in hPSC differentiation into pancreatic β-like cells.The alternative text for this image may have been generated using AI.

A Schematic of the involvement of cell cycle genes MKI67, KIF14, E2F7, SKA1 and SKA3 in hPSC differentiation into pancreatic β-like cells. B Flow cytometry analyses of KI67, KIF14, E2F7, SKA1 and SKA3 across the timepoints of hiPSC differentiation into pancreatic β-like cells. Results are from n = 3 independent experiments. Statistical analyses were conducted with one-way ANOVA with Tukey’s post hoc test and considered to be statistically significant when P ≤ 0.05. C Cell cycle flow cytometry analyses across the timepoints of hiPSC differentiation into pancreatic β-like cells. Results are from n = 3 independent experiments. Statistical analyses were conducted with one-way ANOVA with Tukey’s post hoc test, and considered to be statistically significant when P ≤ 0.05. For all statistical analyses: Error bars represent standard deviation (STDEV).“See also Fig S4”.

Back to article page