Fig. 2: Breast cancer cell lines express AdipoR1, and AdipoRon activates AdipoR1 signaling. | Cell Death & Disease

Fig. 2: Breast cancer cell lines express AdipoR1, and AdipoRon activates AdipoR1 signaling.

From: AdipoR1–AMPK axis suppresses breast cancer across molecular subtypes via multimodal cell death pathways, including ferroptosis and apoptosis

Fig. 2: Breast cancer cell lines express AdipoR1, and AdipoRon activates AdipoR1 signaling.

A AdipoR1 protein expression in MCF7, T47D, MDA-MB-231, and MDA-MB-468 human breast cancer cells. B ADIPOR1 mRNA expression in MCF7, T47D, MDA-MB-231, and MDA-MB-468 human breast cancer cells and EO771 and 4T1-Luc mouse breast cancer cells. C Upper panel: pAMPK and AMPK protein expression in breast cancer cell lines 24 h after AdipoRon (40 µg/mL) exposure. Lower panel: time course of pAMPK and AMPK protein expression in breast cancer cell lines over 1 h after exposure to AdipoRon (40 µg/mL).

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