Table 1 Demographic, biochemical and clinical characteristics of healthy donors and RA patients.

From: Disruption of metabolic licensing by JAK inhibitors constrains CD8 T cell activation and effector function

 

HD

DMARDs-MTX

JAKis

n

9

8

10

Sex (F/M)

7/2

6/2

7/3

Age range (years)

30–58

33-68

30-77

ESR mm/h (median±QD)

 

4 ± 1.5

5.5 ± 8.5

CRP mg/L (median±QD)

 

1.1 ± 9

1.2 ± 2.5

DAS28 (mean ± SD)

 

2.4 ± 1

2.5 ± 1.1

RF (+/−)

 

8/0

10/0

Anti-CCPs (+/−)

 

5/3

9/1

  1. Anti-CCPs anti-cyclic citrullinated proteins, CRP C-reactive protein, DAS disease activity score, DMARDs disease-modifying antirheumatic drugs, ESR erythrocyte sedimentation rate, HD healthy donors, QD quartile deviation, RF rheumatoid factor, Tofa tofacitinib, uTx untreated.
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