Fig. 7: Glioblastoma cells that evade chemoradiotherapy-induced cell death exhibit a bifurcated glycolytic program. | Cell Death & Disease

Fig. 7: Glioblastoma cells that evade chemoradiotherapy-induced cell death exhibit a bifurcated glycolytic program.

From: Glioblastoma cells that evade chemoradiotherapy-induced cell death exhibit a bifurcated glycolytic program

Fig. 7: Glioblastoma cells that evade chemoradiotherapy-induced cell death exhibit a bifurcated glycolytic program.

Schematic research summary depicting that chemoradiotherapy induces a coordinated reorganization of glycolytic metabolism in GBM cells. Surviving cells display increased glucose uptake and enhanced upper glycolytic activity but reduced lower glycolytic enzyme expression and lactate output. This shift promotes the diversion of glycolytic intermediates toward the biosynthetic pathways, such as nucleotide production.

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