Fig. 5: Cell-dependent regulation of TGF-β expression and secretion by 5-FU. | Cell Death Discovery

Fig. 5: Cell-dependent regulation of TGF-β expression and secretion by 5-FU.

From: Regulation of transforming growth factor is involved in the efficacy of combined 5-fluorouracil and interferon alpha-2b therapy of advanced hepatocellular carcinoma

Fig. 5

HuH-7, Hep G2, and AML-12 cells were treated with different concentrations of 5-FU as indicated (a), and 30 µg/mL 5-FU for the indicated time periods (b). TGF-β was detected by western blotting. TGF-β secretion was measured in HuH-7 and Hep G2 cells as described in Materials and Methods (c, d). Results are expressed as the means ± SD (n = 3)

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