Fig. 2: Pathological diagnosis of primary cardiac malignant fibrous histiocytoma (MFH). | Cell Death Discovery

Fig. 2: Pathological diagnosis of primary cardiac malignant fibrous histiocytoma (MFH).

From: Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor

Fig. 2: Pathological diagnosis of primary cardiac malignant fibrous histiocytoma (MFH).The alternative text for this image may have been generated using AI.

Light microscopy (hematoxylin–eosin, HE) presenting the morphology of tumor cells. Immunohistochemical staining positive for Vim (vimentin), CK (cytokeratin), and WT-1 (Wilms' tumor gene 1) and negative for MyoD-1 (myogenic differentiation antigen 1), CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1/CD31), Desmin, S100 (calcium-binding protein), SMA (smooth muscle actin), MSA (muscle-specific Actin), EMA (epithelial membrane antigen), Myogenin, CK5/6 (cytokeratin 5/6), CD34 (hematopoietic progenitor cell antigen CD34), HBME-1 (human mesothelial cell), and PGM-1 (phosphoglucomtase-1). Representative images of the antibody staining are displayed. Scale bars, 100 µm

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