Fig. 5: Recurrent hotspot PI3KCA (H1047) was first identified in cardiac tumor tissue. | Cell Death Discovery

Fig. 5: Recurrent hotspot PI3KCA (H1047) was first identified in cardiac tumor tissue.

From: Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor

Fig. 5: Recurrent hotspot PI3KCA (H1047) was first identified in cardiac tumor tissue.The alternative text for this image may have been generated using AI.

a Sanger sequencing of PIK3CA (His1047Arg) by using blood and tumor tissue samples of Patient-1. b Phosphorylation of Akt Thr 308 site as well as GSK3-beta at Ser9 site was markedly enhanced in cardiac tumor tissues

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