Table 2 Multivariate survival analysis of miR-222-3p expression and disease-free survival

From: Downregulated circulating microRNAs after surgery: potential noninvasive biomarkers for diagnosis and prognosis of early breast cancer

Variable

HR

95% CI of HR

P

MiR-222-3p (low vs. high)

13.186

1.063–163.591

0.045

Age (≤50 vs. >50)

0.279

0.041–1.896

0.192

Histologic tumor size (≤2 cm vs. 2–5 cm vs. >5 cm)

0.228

0.050–1.030

0.055

No. of positive nodes (0 vs. 1–3 vs. ≥4)

1.402

0.399–4.931

0.598

Hormone receptor status (negative vs. positive)

0.547

0.071–4.227

0.564

HER2 status (negative vs. positive)

0.127

0.009–1.155

0.065

Grade (2 vs. 3)

5.052

0.691–36.946

0.111

  1. HR hazard ratio, CI confidence interval, HER2 human epidermal growth factor receptor 2
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