Table 3 Multivariate survival analysis of numbers of highly expressed miRNAs and disease-free survival

From: Downregulated circulating microRNAs after surgery: potential noninvasive biomarkers for diagnosis and prognosis of early breast cancer

Variable

HR

95% CI of HR

P

No. of highly expressed miRNAs (<3 vs. ≥3)

2.293

1.128–4.662

0.022

Age (≤50 vs. >50)

0.397

0.069–2.301

0.303

Histologic tumor size (≤2 cm vs. 2–5 cm vs. >5 cm)

0.224

0.043–1.160

0.074

No. of positive nodes (0 vs. 1–3 vs. ≥4)

1.905

0.444–8.169

0.386

Hormone receptor status (negative vs. positive)

0.476

0.043–5.261

0.545

HER2 status (negative vs. positive)

0.353

0.025–5.011

0.442

Grade (2 vs. 3)

3.060

0.338–27.685

0.320

  1. HR hazard ratio, CI confidence interval, HER2 human epidermal growth factor receptor 2
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