Table 3 Statistical results for network distance analyses

From: An analysis of aging-related genes derived from the Genotype-Tissue Expression project (GTEx)

 

UD versus DD

UD versus UND

DD versus UDD

DD versus DND

UD versus UDD

UDD versus UDND

PPI network

 Median

UU: 3.07

UN: 3.06

DD: 2.68

DN: 2.88

UD: 2.90

UDN: 2.96

 W-value

426,260

192,850

140,320

194,510

255,200

388,610

 P-value

4.47e-117

0.423

2.11e-45

8.79e-47

1.78e-27

7.04e-5

Signaling network

 Median

UU: 3.57

UN: 3.75

DD: 3.74

DN: 3.81

UD: 3.7

UDN: 3.77

 W-value

22,554

406,120

54,985

455,310

44,784

1,804,700

 P-value

0.0040

2.19e-05

0.62

0.046

0.0021

0.018

  1. The network distances were represented by average length of the shortest paths for nodes in each group and compared by Wilcoxon test. For the signaling network, distances were counted from both directions in each distance group
  2. UD network distances between UAG nodes within the group, DD distances between DAG nodes within the group, UDD distances between UAG and DAG node groups, UND distances between UAG and NAG node groups, DND distances between DAG and NAG node groups, UDND distances in UND and DND were added up to UDND group
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