Table 1 List of genes assigned to different groups based on their pathway membership as annotated in Gene Ontology

From: Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes

Gene

Apoptosis (GO:0006915)

Autophagy (GO:0006914)

UPR (GO:0006986)

ATF6

ATF6

 

ATF6

DDIT3

DDIT3

 

DDIT3

EIF2AK3

EIF2AK3

 

EIF2AK3

ATF4

ATF4

 

ATF4

EIF2A

EIF2A

  

HSP90B1

HSP90B1

 

HSP90B1

HSPA5

HSPA5

 

HSPA5

XBP1

XBP1

XBP1

XBP1

AMBRA1

AMBRA1

AMBRA1

 

ATG12

 

ATG12

 

ATG5

ATG5

ATG5

 

ATG7

ATG7

ATG7

 

BCL2L1

BCL2L1

  

BCL2L2

BCL2L2

  

BECN1

BECN1

BECN1

 

MCL1

MCL1

MCL1

 

MTOR

MTOR

MTOR

 

TSC2

TSC2

TSC2

 

BCL2

BCL2

BCL2

 

SQSTM1

SQSTM1

SQSTM1

 

TSC1

 

TSC1

 
  1. Genes from two independent gene expression microarray data sets21, 22 were acquired and analyzed as described in the Materials and methods and Supplementary Table S2, and a gene signature of 21 genes was selected. The GO terms for Autophagy Gene Ontology GO:0006914, Apoptosis Process GO:0006915 and Response to unfolded protein GO:0006986.