Fig. 7: YL064 inhibits myeloma tumor growth in vivo.
From: YL064 directly inhibits STAT3 activity to induce apoptosis of multiple myeloma cells
a, b Mice bearing MM1.S MM tumors were treated with either YL064 (30 mg/kg; IP) or vehicle daily for 9 days. Tumor volume was measured every 2 days (a). Body weight were measured every 2 days (b). c The hematoxylin–eosin staining analysis of tumors. The indicated proteins were examined by immunohistochemistry (IHC) in tumor tissues (c). *p < 0.05, vehicle vs YL064-treated group. Scale bar = 50 μm
