Table 1 Small molecule inhibitors and stressors used in cleaved caspase 3 activity assay to determine the vulnerability of MN9D and N2A cells.
From: Survival of midbrain dopamine neurons depends on the Bcl2 factor Mcl1
Compound | Works as | Concentration (µM) |
|---|---|---|
PAC1 | Caspase-3 activator | 10 |
Etoposide | Topoisomerase inhibitor | 5 |
Bam7 | Bax activator | 10 |
Birinapant | cIAP1 inhibitor /Birc2 inhibitor | 10 |
Lexibulin | Microtubule inhibitor | 1 |
Nutlin-3a | p53 inhibitor | 10 |
YM155 | Mcl1 inhibitor /Survivin inhibitor | 10 |
Obatoclax | Mcl1 inhibitor /Bcl2 inhibitor | 10 |
A1210477 | Mcl1 inhibitor | 10 |
UMI-77 | Mcl1 inhibitor | 10 |
ABT-263 | Bcl-xL inhibitor | 10 |
ABT-199 | Bcl2 inhibitor | 10 |
