Table 2 Effect of metformin (MET) on proliferation of polycystic kidney epithelial cells

From: Low-dose 2-deoxyglucose and metformin synergically inhibit proliferation of human polycystic kidney cells by modulating glucose metabolism

 

0 mM

0.6 mM

2.5 mM

10 mM

40 mM

12 h

100.00 ± 2.89

94.22 ± 1.91*

87.09 ± 1.70***

77.57 ± 2.02***

64.26 ± 1.17***

24 h

100.00 ± 2.56

92.28 ± 1.61**

87.23 ± 2.00***

61.24 ± 1.73***

51.42 ± 0.57***

36 h

100.00 ± 2.35

90.68 ± 1.47**

83.14 ± 4.90***

56.20 ± 1.92***

43.56 ± 1.31***

48 h

100.00 ± 3.21

85.26 ± 2.56***

76.42 ± 3.73***

55.04 ± 1.59***

39.93 ± 1.55***

  1. *P < 0.05, **p < 0.01, ***p < 0.001 vs Control