Table 3 Effects of combined use of 2-deoxyglucose (2-DG) and metformin (MET) on proliferation of polycystic kidney epithelial cells

From: Low-dose 2-deoxyglucose and metformin synergically inhibit proliferation of human polycystic kidney cells by modulating glucose metabolism

 

0 + 0 mM

1.3 + 0.6 mM

2.5 + 1.3 mM

5 + 2.5 mM

10 + 5 mM

12 h

100.00 ± 2.18

85.92 ± 2.15***

73.47 ± 0.94***

68.16 ± 1.98***

58.40 ± 3.25***

24 h

100.00 ± 3.21

80.02 ± 1.00***

68.83 ± 1.22***

56.53 ± 1.20***

43.21 ± 1.05***

36 h

100.00 ± 1.97

73.43 ± 2.52***

63.98 ± 1.44***

55.11 ± 1.78***

40.31 ± 1.30***

48 h

100.00 ± 2.43

67.02 ± 2.00***

56.41 ± 2.04***

44.87 ± 1.35***

35.81 ± 2.12***

  1. *P < 0.05, **p < 0.01, ***p < 0.001 vs Control
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