Table 4 The percentage of WT9-7 cells in G0/G1, S, and G2/M phases

From: Low-dose 2-deoxyglucose and metformin synergically inhibit proliferation of human polycystic kidney cells by modulating glucose metabolism

Group

G0–G1 (%)

S (%)

G2-M (%)

Control

30.71 ± 1.78

35.27 ± 2.05

34.03 ± 2.48

2-DG

37.64 ± 2.50*

25.76 ± 4.03*

36.60 ± 1.92

MET

38.55 ± 2.45*

28.81 ± 1.06**

33.31 ± 1.98

2-DG+MET

58.16 ± 2.32***

21.36 ± 1.52***

20.48 ± 3.25**

  1. Control normal group, 2-DG 2-deoxyglucose-alone group, MET metformin-alone group, 2-DG+MET the combination of 2-DG and metformin
  2. *P <  0.05, **p <  0.01, ***p <  0.001 vs Control, n = 3
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