Fig. 1: MHT rescues neurons from CA/CPR and OGD/R both in vivo and in vitro. | Cell Death Discovery

Fig. 1: MHT rescues neurons from CA/CPR and OGD/R both in vivo and in vitro.

From: Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy

Fig. 1: MHT rescues neurons from CA/CPR and OGD/R both in vivo and in vitro.The alternative text for this image may have been generated using AI.

a MHT improves the 72 h survival rate of mice after CA/CPR following ROSC from KCL-induced CA. b MHT reduces cell death in cortex after ROSC for 72 h. c MHT reduces apoptosis in cortex after ROSC for 72 h (scale bar 100 µm). d MHT reduces primary cortical neuron death after OGD/R for 24 h. NT normothermia, MHT mild hypothermia therapy, ROSC return of spontaneous circulation, OGD/R oxygen glucose deprivation and reperfusion. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001, vs. NT

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